Sponsored by the
European Commission
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European Society for Mathematical
and Theoretical Biology
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Biomathematics Euro Summer School
Dynamical Systems in Physiology and Medicine
Urbino (Italy) July 8-19, 2002
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More scholarships available registration procedure/updated registration procedure
For more details please write to info@biomatematica.it
Some school photos are available
Participants' e-mail address
Organization
The School is organized by the EuroMediterranean BioMathematics Association (EMBMA),
by the Centro Interuniversitario di Matematica Applicata a Biologia, Medicina e Ambiente
(CIMAB) and by the Istituto Analisi dei Sistemi ed Informatica "A. Ruberti" (IASI)
of the Italian Consiglio Nazionale delle Ricerche (CNR). It is endorsed by the European
Society for Mathematical and Theoretical Biology (ESMTB) and sponsored by the European
Commission, by IASI, by the Progetto Strategico Biomatematica of CNR, by the Societe'
Francaise de Biologie Theorique (SFBT).
Scientific Committee
Luis Abia, Ovide Arino, Alain Bardou, Jacques Belair, Edoardo Beretta, Rodolfo Bermejo, George Cremona, Andrea De Gaetano, Oliver Jensen,
Yang Kuang, Andre' Longtin, Philip Maini, Andrea Mari, Khashayar Pakdaman, Fortunata Solimano, Yasuhiro Takeuchi
Organizing Committee
Ovide Arino, Edoardo Beretta, Andrea De Gaetano (Managing Director), Simona Panunzi, Fortunata Solimano
The Urbino Euro Summer School follows closely its sister event 5 th European Conference on Mathematical and Theoretical Biology (ECMTB2002). Participation to both events is encouraged.
PROGRAMME
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Periodic haematological diseases (10 units)
Coordinator: Jacques Belair, University of Montreal, Quebec, Canada
Other instructors: Joseph Mahaffy, San Diego State University
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Teaching units: |
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Periodic Haematological Diseases: Pathology, Modelling,and Treatment (two units).
Peripheral Control of Red Blood Cell Production (two units)
Peripheral Control of White Blood Cell Production (two units).
Stem Cell Dynamics: Understanding Cyclical Neutropenia and Periodic Leukaemia (two units).
Regulation of Platelet Production by Thrombopoietin (two units).
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Modelling and cellular automata in the study of cardiac arrhythmias and ventricular fibrillation (8 units)
Coordinator: Alain Bardou, INSERM/University of Rennes 1, Rennes, France
Other instructors: Pierre Auger, Universite` Lyon 1, France
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Teaching units: |
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Historical perspective and a summary of notions of cardiac electrophysiology
The main problems related to the rhythm and ventricular fibrillation
Models of cardiac cellular activity
Models for the propagation at the tissular level. Implications in novel therapeutic strategies and risk prevention (two units).
TBA (two units).
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Modelling aspects of airflow and gas exchange in the lung (8 units)
Coordinator: George I. Cremona, Ospedale Università San Raffaele, Milano, Italy
Other instructors: Oliver Jensen, Applied Mathematics, University of Nottingham, UK |
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Teaching units: |
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Flow through deformable airways (two units)
Wheezing and other musical aspects of flow in the airways (two units)
Nitric oxide - a simple molecule of many talents (two units)
Modelling Pulmonary nitric oxide exchange dynamics (two units)
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Models for the Glucose-Insulin system (10 units)
Coordinators: Andrea De Gaetano, CNR IASI Roma, Italy, Andrea Mari, CNR LADSEB Padova
Other instructors: Jeppe Sturis, NovoNordisk Pharmaceuticals, DK, Jacques Belair, University of Montreal, Quebec, Canada.
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Teaching units: |
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Basic physiology of energy metabolism.
Non-linear model of ultradian oscillations in glucose and insulin
Frequency-locking behavior - comparison of model simulations and clinical experiments
Bifurcation behavior of oscillatory glucose/insulin models
Glucose kinetics and insulin resistance. Need for quantitative assessment. The euglycemic hyperinsulinemic clamp.
Tracer kinetics and models at steady state: compartmental and circulatory models.
Tracer kinetics and models in non-steady state: compartmental and circulatory models.
Models for insulin sensitivity: the minimal model.
Multi-compartment and circulatory models.
Delay differential models.
Multiple delayed regulatory loops.
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Neuronal modeling (10 units)
coordinator: K. Pakdaman, INSERM Paris, France |
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Teaching units: |
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Overview on neuronal models I From threshold devices to Hodgkin-Huxley models
Overview on neuronal models II Compartmental models
Synaptic dynamics
Neuronal coding I Are neurons reliable?
Neuronal coding II A possible biomedical application enhanced sensitivity through stochastic resonance
Neuronal coding III Information theoretic approach
Neuronal assemblies: How can neurons synchronise their firing?
Functional applications I Modelling the electrosensory system of electric fish
Functional applications II Modelling a pathology
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Delay Differential Equations (14 units)
Coordinator: Edoardo Beretta, Istituto di Biomatematica, Università degli Studi di Urbino, Urbino, Italy
Other instructors:
Mostafa Adimy, Dept. de Mathématiques, Université de Pau et des Pays de l'Adour, Pau, France.
Ovide Arino, Université de Pau and IRD Bondy, Bondy, France
Uwe an der Heiden, Institute of Mathematics and Theory of Complex Systems, Universität Witten/Herdecke, Witten, Germany.
Shigui Ruan, Dept. of Mathematics and Statistics, Dalhousie University, Halifax, Nova Scotia, Canada
Yasuhiro Takeuchi, Dept. of Systems Engineering, Faculty of Engineering, Shizuoka University, Hamamatsu, Japan.
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Teaching units: |
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Linear theory of delay differential equations: introductory theory (three units)
Nonlinear delay differential equations: semilinear theory and some recent advances in the geometry of curves, surfaces and manifolds determined by delay differential equations (three units)
Stability switches in delay differential systems with delay dependent parameters (three units);
On the dynamics of nonlinear feedback loops with applications to cellular, physiological and sensory systems (two units);
Infection models with delay (two units);
Time-delayed chemostat models for bacteria and virulent phages.
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Numerical methods (10 units)
Coordinator: Rodolfo Bermejo, Universidad Complutense, Madrid, Spain
Other instructors: Luis Abia, Department of Mathematics, University of Valladolid
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Teaching units: |
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Numerical integration of ODE's: simple methods, pitfalls and diagnostics (two units)
Variable step/ variable order methods (two units)
Integrators for stiff systems and further ODE integration problems (two units)
Basic finite differences methods for PDE's (two units)
Integration of PDE's for age-structured problems
Numerical integration of DDE's
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ESMTB
EMBMA
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C.N.R.
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